【关键词】 注射剂;磷酸钙类;骨粘合剂;纤维蛋白组织粘着剂;骨形态发生蛋白质类;载体;骨诱导
【Abstract】 AIM: To evaluate the feasibility of injectable calcium phosphate cement (ICPC) and fibrin sealant (FS) as an injectable compound carrier of bone morphogenic protein (BMP) . METHODS: The composites of ICPC/FS/bBMP, ICPC/FS or bBMP were injected subcutanously or implanted into thigh muscle pouches of 45 mice at effect of ecto RESULTS: ICPC/FS/bBMP composite induced the formation of new bone most effectively. BBMP stimulated cess osteogenesis while ICPC/FS showed no sign of new bone e was a significant difference among them (P